ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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KLOW - GHK-Cu (50mg) / KPV (10mg) / BPC-157 (10mg) / TB500 (10mg)

KLOW - GHK-Cu (50mg) / KPV (10mg) / BPC-157 (10mg) / TB500 (10mg)

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What is KLOW - GHK-Cu (50mg) / KPV (10mg) / BPC-157 (10mg) / TB500 (10mg)?

KLOW is a research-only, multi-peptide formulation composed of four scientifically recognized peptides: GHK-Cu, KPV, BPC-157, and TB-500. These compounds are widely studied for their potential roles in modulating tissue repair, inflammation, cellular signaling, and regenerative processes under controlled laboratory conditions.

GHK-Cu is a naturally occurring copper-binding tripeptide with strong gene-regulatory properties, influencing numerous biological processes such as wound contraction, angiogenesis, and fibroblast activation [1].

KPV is a tripeptide fragment of α-MSH, characterized by its anti-inflammatory effects and inhibition of pro-inflammatory cytokine production [2].

BPC-157 is derived from a protective gastric peptide, and has been studied in preclinical settings for its ability to enhance vascularization and promote tendon, ligament, and muscle regeneration [3].

TB-500, a synthetic fragment of thymosin β-4, has been investigated for its role in actin regulation, cell migration, and tissue architecture remodeling [4].

KLOW is intended strictly for scientific and laboratory research, including in vitro experimentation and preclinical investigation.

Chemical Structure of KLOW - GHK-Cu (50mg) / KPV (10mg) / BPC-157 (10mg) / TB500 (10mg)

Each peptide in KLOW is composed of a distinct amino acid sequence, designed for targeted biological activity:

  • GHK-Cu: Gly-His-Lys complexed with Cu²⁺. This peptide chelates copper ions, essential for its regenerative signaling capacity [1].
  • KPV: Lys-Pro-Val, a tripeptide segment of α-MSH, known to penetrate cells via peptide transporters like PepT1 [2].
  • BPC-157: A 15-amino acid sequence (GEPPPGKPADDAGLV), stabilized for research purposes, derived from a partial sequence of human gastric protein [3].
  • TB-500: A synthetic 17-amino acid peptide segment of thymosin β-4 (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Thr), designed to mimic its cellular repair and migration functions [4].

This formulation does not contain excipients or delivery agents, ensuring high-purity peptides suitable for controlled laboratory use.

What Are the Effects of KLOW - GHK-Cu (50mg) / KPV (10mg) / BPC-157 (10mg) / TB500 (10mg)?

In preclinical models, each component of KLOW has demonstrated distinctive but complementary effects:

  • GHK-Cu has shown to upregulate genes related to collagen synthesis, antioxidant defense, and angiogenesis. It also supports tissue remodeling by influencing fibroblast proliferation and immune response regulation [1].
  • KPV exhibits potent anti-inflammatory effects by suppressing pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β via intracellular signaling inhibition [2].
  • BPC-157 enhances endothelial repair and neovascularization, particularly in models of soft tissue damage. It interacts with nitric oxide pathways and has shown support for tendon and muscle repair [3].
  • TB-500 facilitates cellular migration and actin cytoskeleton reorganization, contributing to improved muscle regeneration, wound repair, and extracellular matrix formation [4].

Collectively, these peptides offer a multi-targeted platform for researchers exploring tissue repair dynamics, inflammation resolution, and regenerative mechanisms in biological systems.

Citations:

  1. Pickart, L. et al. “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International Journal of Molecular Sciences, 2018, 19(7), 1987.
  2. Bilsborough, J. et al. “KPV peptide inhibits inflammatory cytokine production via PepT1 in epithelial cells.” Gastroenterology, 2007, 133(4), 1362–1375.
  3. Sikiric, P. et al. “BPC 157 and Healing: New Therapeutic Insights.” Current Pharmaceutical Design, 2018, 24(18), 1980–1989.
  4. Huff, T. et al. “Thymosin beta-4 is involved in cell migration, angiogenesis, and wound healing.” Annals of the New York Academy of Sciences, 2007, 1112(1), 234–246

COA

Certificate of Analysis

HPLC

High Performance Liquid Chromatography

High Quality - 99% Purity Guaranteed

Product Quality Guarantee

We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
HPLC TEST FEE
$100
PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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