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Premium Weight Loss Bundle

Premium Weight Loss Bundle

$337.50
$375.00 $337.50
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The Premium Weight Loss Bundle (PWLB) is a dual-compound formula designed for research into metabolic regulation, appetite control, and neurochemical mechanisms: 

  • GLP‑1 T: A dual agonist targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide‑1 (GLP‑1) receptors. Preclinical rodent studies demonstrate that tirzepatide reduces body weight primarily by decreasing caloric intake, reducing meal size/frequency, and shifting macronutrient preference toward low-fat options [1]. Additional mouse model data indicates tirzepatide suppresses preference for palatable foods such as lipids [2]. 

  • Tesofensine Tablets: A phenyltropane-based triple monoamine reuptake inhibitor (DAT/NET/SERT) studied for its effects on energy regulation and neuroplasticity. In preclinical rodent models, tesofensine increased hippocampal expression of brain-derived neurotrophic factor (BDNF) and the synaptic plasticity marker Arc after sub-chronic and chronic administration [3]. 

This bundle supports preclinical exploration across appetite suppression, metabolic balance, and neurochemical adaptation pathways. It is ideal for studies into feeding behavior, weight regulation, and neurotrophic changes in experimental models. 

 This bundle is intended for laboratory research purposes only.


Citations

  1. Cosgrove R, Antonellis MP, et al. “Tirzepatide mediates its anorexigenic effect in mice due to reductions in homeostatic and reward-related feeding.” Diabetes. 2020;69(Supplement_1):142‑OR. 
  2. Hayes‑Lab et al. “Tirzepatide suppresses palatable food intake by selectively reducing lipid consumption in rodent two-diet choice model.” Europe PMC. 2022. 
  3. Scheel‑Krüger J, Moldt P, Watjen F. “Expression of BDNF and Arc mRNA in rat hippocampus after sub‑chronic and chronic tesofensine treatment.” Eur J Pharmacol. 2007;572(2-3):150‑157. 
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.