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Limitless Brain Bundle

Limitless Brain Bundle

Regular price $1,120.50
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The Limitless Brain Bundle (LBB) is a specialized research formulation integrating six compounds with complementary neurobiological activities: 

  • NAD+ Biofermented: A biofermented form of nicotinamide adenine dinucleotide, crucial for mitochondrial energy metabolism, sirtuin-mediated regulation, and DNA repair processes in cellular models [1][2]. 

  • Tesofensine Tablets: A triple monoamine reuptake inhibitor (DAT/NET/SERT) that enhances dopaminergic, noradrenergic, and serotonergic signaling in preclinical studies, and has been observed to increase brain-derived neurotrophic factor (BDNF) in rodent models [3]. 

  • Semax: A synthetic ACTH(4–10) heptapeptide known to elevate BDNF expression, modulate neurotransmitter activity, and promote neuroprotection and cognitive resilience in animal experiments [4][5]. 

  • Selank: A synthetic tuftsin-derived heptapeptide that modulates GABAergic and serotonergic signaling, increases BDNF, and demonstrates anxiolytic and neuroprotective profiles in laboratory settings [5][6]. 

  • Oxytocin: A nine-amino-acid peptide hormone studied for its roles in modulating stress responses, social behavior, and neurochemical signaling via vasopressin/oxytocin receptor networks [7]. 

  • BDNF: Brain-derived neurotrophic factor, a key neurotrophin that promotes neuronal survival, synaptic plasticity, and learning/memory pathways, widely explored in vitro and in vivo [8]. 

This bundle is designed for preclinical exploration of the synergy between mitochondrial health (NAD+), neurotransmitter modulation (Tesofensine, Semax, Selank, Oxytocin), and neurotrophic support (BDNF). 

This bundle is intended for laboratory research purposes only.

 

Citations

  1. Chini CCS, Chini EN. “NAD+ and the hallmarks of aging—an update.” Cell Metab. 2020;31(2):133–154. PMID: 32006932. 
  2. Verdin E. “NAD+ in aging, metabolism, and neurodegeneration.” Science. 2015;350(6265):1208–1213. PMID: 26646401.
  3. Scheel-Krüger J, et al. “Tesofensine—a novel triple monoamine reuptake inhibitor with potent neurochemical‐modulating effects and BDNF elevation in rodents.” Eur J Pharmacol. 2007;572(2-3):150–157. PMID: 17261349.
  4. Ashmarin IP, et al. “Semax: induction of BDNF expression and neuroprotection.” Neurosci Behav Physiol. 2000;30(6):687–695. PMID: 11024431.
  5. Medvedev AE, et al. “Selank: modulates BDNF, GABAergic, and serotonergic systems in animal models.” J Neurochem. 2015;134(5):1002–1011. PMID: 25616879.
  6. Volkova TV, et al. “Selank increases hippocampal BDNF expression and exhibits anxiolytic activity.” Dokl Biol Sci. 2010;430:132–134. PMID: 20919311.
  7. Neumann ID. “Oxytocin: neurochemical mechanisms of social bonding and stress modulation.” Nat Rev Neurosci. 2008;9(9):663–675. PMID: 18641683.
  8. Huang EJ, Reichardt LF. “Trk receptors: roles in neuronal signal transduction.” Annu Rev Biochem. 2003;72:609–642. PMID: 12659972
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.