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Kisspeptin (10mg)

Kisspeptin (10mg)

$99.00
$99.00
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is Kisspeptin (10mg)?

Kisspeptin refers to a family of neuropeptides derived from the KISS1 gene, most notably kisspeptin-54, -14, -13, and -10—all sharing a common C-terminal Arg-Phe-NH₂ motif and acting as ligands of the G-protein coupled receptor GPR54 (also known as Kiss1R) [1][2]. First identified as a metastasis suppressor, kisspeptin has since been shown in laboratory studies to be a crucial regulator of the hypothalamic–pituitary–gonadal (HPG) axis—potently stimulating gonadotropin-releasing hormone (GnRH) neurons, which triggers secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1][3][4].

Chemical Structure of Kisspeptin (10mg)

Kisspeptin consists of the 10–amino acid sequence Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Phe (YNWNSFGLRF), featuring a conserved Arg–Phe–NH₂ motif that is critical for receptor binding and biological activity. The peptide has a molecular formula of C₆₃H₈₃N₁₇O₁₄ and a molecular weight of approximately 1,302.4 Da, as confirmed by PubChem (CID 25240297). It is also referred to by several synonyms, including KISS‑1, metastin, and Kp‑10 peptide [1][2][5].

What Are the Effects of Kisspeptin (10mg)?

GnRH and Gonadotropin Release:

Central or peripheral administration of kisspeptin in rodents and humans consistently induces GnRH secretion, followed by LH and FSH elevation—a foundational mechanism in HPG axis research [3][5]. 

Puberty Onset Mechanism:

Kisspeptin–GPR54 signaling is essential for initiating puberty; genetic defects in either component result in hypogonadotropic hypogonadism in both animal models and humans [3]. 

Metastasis Suppression:

Originally identified as a metastin, kisspeptin reduces cancer cell invasiveness in laboratory assays [1]. 

Sexual Behavior and Desire:

Infusion studies in human subjects reveal kisspeptin modulates neural circuits associated with sexual arousal and attraction—bridging basic reproductive signaling with behavioral correlates in research settings [6][7]. 

Cardiometabolic Regulation:

Emerging evidence in rodent models highlights kisspeptin’s role in metabolic signaling, appetite regulation, body weight maintenance, and cardiovascular function [2][8]. 


Citations

  1. PubChem Compound Summary for Kisspeptin‑10 (CID 25240297): sequence YNWNSFGLRF; molecular data and synonyms. 
  2. de Roux N, et al. “Hypogonadotropic hypogonadism due to loss of function of the KiSS1‑derived peptide receptor GPR54.” Proc Natl Acad Sci USA. 2003;100(19):10972–10976. PMID: 13129905. 
  3. Chan YM, et al. “GPR54 is essential for Gonadotropin‑releasing hormone–induced puberty.” Nature. 2008;456(7218):188–193. PMID: 18924107. 
  4. Han SK, et al. “Activation of gonadotropin‑releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.” J Neurosci. 2005;25(49):11349–11356. PMID: 16306473. 
  5. Dhillo WS, et al. “Kisspeptin‑54 stimulates the hypothalamic‑pituitary gonadal axis in human studies.” J Clin Invest. 2005;115(12):3271–3279. PMID: 16249535. 
  6. Mills EG, et al. “Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.” JAMA Netw Open. 2022;5(10):e2233170. 
  7. Mills EG, et al. “Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder.” JAMA Netw Open. 2023;6(2):e2250192. PMID: 36735255. 
  8. Tomikawa J, et al. “Kisspeptin modulates energy expenditure and body weight in mice.” Endocrinology. 2018;159(8):3127–3139. PMID: 29877287. 

COA

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HPLC

High Performance Liquid Chromatography

High Quality - 99% Purity Guaranteed

Product Quality Guarantee

We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
HPLC TEST FEE
$100
PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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