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BDNF (Brain-derived neurotrophic factor) (10mg)

BDNF (Brain-derived neurotrophic factor) (10mg)

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is BDNF (Brain-derived neurotrophic factor) (10mg)?

Brain‑derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that supports neuronal survival, differentiation, and synaptic plasticity [1][3]. It signals primarily through the high-affinity TrkB receptor and also interacts with the p75NTR receptor [1][2]. Preclinical research has shown that BDNF plays a critical role in promoting neurogenesis, dendritic spine formation, and long-term potentiation—making it an essential tool for studies in neurodevelopment, synaptic function, and CNS adaptability [1][2][3].

Chemical Structure of BDNF (Brain-derived neurotrophic factor) (10mg)

BDNF is synthesized as a 247‑amino‑acid precursor (proBDNF), which is proteolytically processed to the mature 119‑amino‑acid form [4]. The functional, biologically active form is a 27‑kDa homodimer, held together by disulfide bonds between conserved cysteine residues [4][5].

What Are the Effects of BDNF (Brain-derived neurotrophic factor) (10mg)?

Synaptic Plasticity & Cognitive Enhancement:

BDNF is essential for long-term potentiation (LTP), long-term depression (LTD), dendritic spine maturation, and neural circuit adaptations—underpinning learning and memory in research models [1][3]. 

Neurogenesis & Structural Brain Remodeling:

It fosters survival and proliferation of hippocampal and cortical neurons, contributing to adult neurogenesis and neural architecture reconstruction [1][2][3]. 

Neuroprotection & Anti‑Degeneration:

In vitro and in vivo studies support BDNF’s ability to protect neurons from apoptosis, oxidative stress, and excitotoxic injury, making it a key agent in neuroprotective research [1][5]. 

Peripheral & Endothelial Modulation:

Beyond the CNS, BDNF exhibits paracrine roles in endothelial cells and peripheral tissues—regulating vascular function, metabolism, and angiogenesis [6]. 

Exercise‑Linked Neuroplasticity:

Physical activity elevates endogenous BDNF levels, facilitating exercise-induced neuroplastic adaptation, improved mood, and cognitive resilience in animal models [7]. 

Citations

  1. MDPI Int J Mol Sci. “Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential.” 2020;21(20):7777. 
  2. Frontiers in Aging Neuroscience. “The role of brain‑derived neurotrophic factor in central nervous system.” 2022;14:986443. 
  3. Kowiański P, et al. “BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity.” Cell Mol Neurobiol. 2017;38:579–593. 
  4. Current Biology. “BDNF is a basic, homodimeric, secretory protein with molecular mass ∼27 kDa.” 2002. 
  5. ScienceDirect (Neurobiology). “BDNF is a polypeptide of 119 amino acid residues, forming a homodimer.” 2019. 
  6. J Biol Chem. “Paracrine and autocrine functions of BDNF in endothelial cells.” 
  7. Translational Medicine Biomed Central. “Circulating BDNF as a potential biomarker for neuroplasticity post-stroke.” 2022;20:3312-y. 

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HPLC

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Product Quality Guarantee

We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
HPLC TEST FEE
$100
PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

Customer Reviews

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Enrique Escribano
BDNF

The BDNF is extremely high quality. You can feel the antidepressant and mental sharpness right away. Tosses the blood brain barrier no problem. Price is decent for such an expensive compound. Shipping was fast and well protected and packaged. Solid company.