Tesmoralin
Tesamorelin, an analog of growth hormone releasing hormone, has demonstrated the ability to elevate IGF-1 levels by an average of 181 micrograms/liter. It binds to and activates human GHRH receptors with a potency akin to endogenous GHRH. Beyond these effects, Tesamorelin offers a range of benefits, including nootropic properties and the reduction of triglycerides. Recent research has revealed its capacity to decrease carotid intima media thickness (cIMT), visceral adipose tissue (VAT), and C-reactive proteins (CRP). Importantly, Tesamorelin has not exhibited a significant impact on other pituitary hormones and their respective mechanisms in the body. Moreover, studies have indicated its potential to enhance cognitive function.
Ipamorelin
Ipamorelin is recognized as a selective GH-Secretagogue and an agonist for ghrelin receptors. Its ghrelin stimulation potency is comparable to GHRP6 but with fewer appetite-stimulating properties. Notably, it distinguishes itself by avoiding the release of significant volumes of cortisol, acetylcholine, prolactin, and aldosterone, setting it apart as the first selective GH-Secretagogue. The combination of Ipamorelin and Tesamorelin offers the potential for enhanced effects, leveraging their distinct mechanisms to stimulate the growth hormone axis synergistically. This synergistic action prompts the pituitary gland to naturally produce and release growth hormone at more youthful levels. Research indicates that this combination yields benefits such as improved deep sleep, reduced triglycerides, visceral adipose tissue, and carotid intima media thickness, enhanced cognition, and overall improved metabolic function.
Ipamorelin and Tesamorelin demonstrate minimal side effects, exhibit low oral and excellent subcutaneous bioavailability in mice. These peptides are available for purchase at Paramount Peptides for educational and scientific research purposes only. Interested buyers should ensure they are licensed researchers before acquiring Ipamorelin and Tesamorelin.
MGF (IGF-IEc)
Mechano-growth factor, also known as the IGF-1Eb isoform of IGF-1, plays crucial roles in muscle remodeling, cellular proliferation, and cellular survival. Recent studies indicate that this specific isoform has the additional capability to activate satellite cells in skeletal muscle, safeguard neurons, and counteract the muscle-wasting effects associated with aging.
MGF primarily functions in the acute repair of muscles, especially after exercise or injury. Studies in rats demonstrate a significant surge in MGF concentrations following muscle injury, and its presence in muscle strongly correlates with the growth and differentiation of skeletal muscle cells.
