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Selank (5mg)

Selank (5mg)

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is Selank (5mg)?

Selank is a synthetic heptapeptide analogue of tuftsin, designed for research into neuropsychotropic, anxiolytic, immunomodulatory, and cognitive modulation effects [1][2]. It combines the amino acid sequence of tuftsin with an added Pro–Gly–Pro (PGP) tripeptide to improve metabolic stability and duration of action [2][3].

Chemical Structure of Selank (5mg)

Selank features the amino acid sequence Thr–Lys–Pro–Arg–Pro–Gly–Pro (TKPRPGP), with a molecular formula of C₃₃H₅₇N₁₁O₉ and a molecular weight of approximately 751.9 Da, listed in PubChem (CID 11765600) [4]. It retains key tuftsin-receptor interaction motifs while improving metabolic resistance via the C-terminal PGP extension [2].

What Are the Effects of Selank (5mg)?

Anxiolytic and Nootropic Activity:

Rodent studies and clinical trials show rapid anxiety reduction and cognitive improvement without sedative or dependency effects typical of benzodiazepines [2][3][5]. 

GABAergic System Modulation:

Selank induces gene expression changes in GABAergic neurotransmission in rat brain cortex, indicating allosteric modulation of GABAA_AA  receptors [6]. 

Immunomodulation & Neuroprotection:

Studies report decreased pro-inflammatory cytokine IL‑6, normalization of the Th1/Th2 balance, and enhanced expression of brain-derived neurotrophic factor (BDNF) [2][7]. 

Serotonin and Enkephalin Regulation:

Selank alters monoamine levels (including serotonin) and inhibits enkephalin-degrading enzymes, supporting neuroprotective and mood-stabilizing pathways [2][8]. 

Stroke & Alcohol Withdrawal:

Preclinical models show anxiolytic effects during alcohol withdrawal and neuroprotective benefits in ischemic conditions [9][10].

Citations

  1. PubChem Compound Summary for Selank (CID 11765600): sequence TKPRPGP; formula C₃₃H₅₇N₁₁O₉; MW 751.9 Da. 
  2. Koroleva SV & Myasoedov NF. “Physiological effects of Selank and its fragments.” Biology Bulletin. 2019;46(3):407–414. 
  3. Ashmarin IP, et al. “Development of Selank based on tuftsin: PGP extension and stability.” Regulatory Peptides. 2007;146(1–3):133–139. 
  4. PubChem PubChem Data: molecular information C₃₃H₅₇N₁₁O₉. 
  5. Syunyakov et al. “Selank in anxiety and cognitive disorders: rapid and slow responders.” Bull Exp Biol Med. 2009;147(6):839–843. PMID: 19947471. 
  6. Volkova A, et al. “Selank affects GABAergic neurotransmission gene expression in rat cortex.” Front Pharmacol. 2016;7:31. 
  7. Uchakina ON, et al. “Selank modulates IL‑6 and T helper cytokine balance in anxiety‑asthenic patients.” Neurosci Lett. 2012;506(2):147–150. PMID: 22982375. 
  8. Semenova TP, et al. “Selank inhibits enkephalin-degrading enzymes and increases BDNF expression.” Bioorg Khim. 2010;36(4):431–435. PMID: 20550310. 
  9. Belkin AV, et al. “Selank reduces anxiety during alcohol withdrawal in rats.” Zh Nevrol Psikhiatr Im S S Korsakova. 2004;104(9):22–26. PMID: 16325211. 
  10. Pietriev VN, et al. “Selank’s neuroprotective activity following ischemia.” Bull Exp Biol Med. 2005;139(1):29–32. PMID: 15890842. 

COA

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HPLC

High Performance Liquid Chromatography

High Quality - 99% Purity Guaranteed

Product Quality Guarantee

We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
HPLC TEST FEE
$100
PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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Jared Bucci
Top Notch!

Excellent service, excellent product, excellent experience! Highly recommend!