GHK-Cu (50mg)

Wound Healing and Tissue Regeneration:

In animal studies, GHK‑Cu promotes fibroblast migration, collagen synthesis, and angiogenesis, leading to accelerated tissue repair [3][5]. 

Anti‑Inflammatory and Antioxidant Effects:

Research shows GHK‑Cu can upregulate antioxidant enzymes such as superoxide dismutase and reduce pro-inflammatory cytokines, protecting tissues from oxidative stress [2][5]. 

Gene Expression Modulation:

GHK‑Cu influences the expression of over 400 human genes related to tissue repair, immune response, and proteostasis, as reported in genomic studies [4]. 

Matrix Metalloproteinase Regulation:

It has been observed to balance MMP activity, thereby protecting extracellular matrix components during the healing process [3][5]. 

Citations

1. Pickart, L., & Thaler, M. M., “Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver,” Nature, vol. 243, no. 5400, pp. 85–87, 1973. 
2. Maquart, F. X., et al., “Stimulation of collagen synthesis in fibroblast cultures by the tripeptide–copper complex GHK-Cu,” FEBS Letters, vol. 238, no. 2, pp. 343–346, 1988. 
3. Pickart, L., “The human tri-peptide GHK and tissue remodeling,” Journal of Biomaterials Science, Polymer Edition, vol. 19, no. 8, pp. 969–988, 2008. 
4. Pickart, L., Vasquez-Soltero, J. M., & Margolina, A., “GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration,” BioMed Research International, vol. 2015, Article ID 648108. 
5. Siméon, A., et al., “Copper-binding tripeptide GHK-Cu stimulates tissue remodeling and angiogenesis,” Wound Repair and Regeneration, vol. 12, no. 1, pp. 50–57, 2004.