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Epithalon (50mg)

Epithalon (50mg)

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is Epithalon (50mg)?

Epithalon—also known as Epitalon, Epithalone, or AEDG peptide—is a synthetic tetrapeptide derived from the pineal gland polypeptide epithalamin, first developed in Russia during the 1980s by Professor Vladimir Khavinson’s team [2][4]. Comprised of the four amino acids alanine, glutamic acid, aspartic acid, and glycine, it is primarily studied for its impact on cell cycle regulation, telomerase activation, and longevity mechanisms in preclinical and limited clinical settings [2][4].

Chemical Structure of Epithalon (50mg)

Epithalon is a tetrapeptide with the sequence Ala–Glu–Asp–Gly, a molecular formula of C₁₄H₂₂N₄O₉, and a molecular weight of ~390.35 Da, as confirmed by PubChem (CID 219042) and IPSS monograph data [1][4]. Structural variants with alternate peptide bonds are rare; most studies utilize the canonical α-bonded form in its free-base or acetate salt form [2][4].

What Are the Effects of Epithalon (50mg)?

Telomerase Activation & Telomere Support:

In vitro studies show Epithalon activates telomerase and prolongs the proliferative lifespan of human somatic cells—extending beyond the Hayflick limit [2][4]. 

Longevity and Anti-Aging Effects:

In murine and insect models, Epithalon reduces mortality rates (e.g., 52% in fruit flies) and extends lifespan in mice, rats, and Drosophila through genomic stabilization and antioxidant activity [2][4]. 

Antioxidant and DNA Integrity:

Research demonstrates Epithalon enhances antioxidant defense (e.g., glutathione peroxidase), reduces DNA damage and chromosomal aberrations in accelerated-aging models [4]. 

Oncostatic Activity:

Animal trials reveal Epithalon suppresses spontaneous mammary and other tumors, possibly via telomerase regulation and oncogene expression control [3][4]. 

Pineal/Glandular Signaling & Melatonin Regulation:

Studies in elderly rats and primates show normalized melatonin production and cortisol rhythms following Epithalon treatment, suggesting circadian influence [2][4]. 

Citations

  1. PubChem CID 219042, “Epitalon Compound Summary” (sequence, formula, molecular weight). 
  2. “Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Telomere Regulation,” International Journal of Molecular Sciences, 2025 (MDPI review of in vitro, in vivo, and mechanistic studies). 
  3. “Epithalon—a geroprotective agent with anti-cancer effect,” R&D Peptide article detailing telomerase modulation and tumor suppression in animal models. 
  4. International Peptide Society Monograph, “Epithalon” PDF—summarizes sequence, telomerase activity, antioxidant properties, tumor suppression, circadian and melatonin effects. 

COA

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HPLC

High Performance Liquid Chromatography

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We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
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PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.