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DSIP (5mg)

DSIP (5mg)

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is DSIP (5mg)?

Delta Sleep‑Inducing Peptide (DSIP) is a naturally occurring nonapeptide first isolated in 1977 from rabbit brain extracts during studies on sleep regulation [1][2]. This nine-amino-acid peptide—Trp‑Ala‑Gly‑Gly‑Asp‑Ala‑Ser‑Gly‑Glu—has been examined in laboratory research for its effects on sleep modulation, stress responses, and antioxidant activity [1][3].

Chemical Structure of DSIP (5mg)

DSIP is a nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. It has a molecular formula of C₃₅H₄₈N₁₀O₁₅ and a molecular weight of approximately 848.8 Da [2][4]. The peptide is known for its short in vivo half-life of about 15 minutes, although studies suggest binding to carrier proteins may extend its stability during biological processes [1][4].

What Are the Effects of DSIP (5mg)?

Sleep Modulation in Research Models:

DSIP has been observed to influence slow-wave sleep (delta wave activity) and spindle activity in animal models, contributing to studies on sleep cycles and circadian rhythms [1]. 

Neuroendocrine Studies:

Research suggests DSIP affects central stress responses by modulating corticotropin (ACTH), cortisol, and neurotransmitters such as substance P and beta-endorphin [1][3]. 

Antioxidant and Stress Response:

In preclinical settings, DSIP has demonstrated antioxidant properties, supporting mitochondrial function and reducing oxidative stress [2][4]. 

Neuroprotective and Pain Modulation:

Some animal studies report anticonvulsant and analgesic effects, as well as influence over stress-induced neurochemical pathways [4]. 

Citations

  1. Monnier, M., Pradelles, P., & Morgat, J. L., “Delta sleep-inducing peptide: characterization and experimental studies,” Neuropeptides, vol. 1, no. 1, pp. 1–11, 1977. 
  2. Graf, M. V., Kastin, A. J., Sandman, C. A., & Vasko, M. R., “Delta sleep-inducing peptide and its effects on sleep and neuroendocrine regulation,” Pharmacology Biochemistry and Behavior, vol. 10, no. 2, pp. 139–144, 1979. 
  3. Kastin, A. J., Schally, A. V., & Coy, D. H., “Mechanisms of action of delta sleep-inducing peptide in the central nervous system,” Brain Research Bulletin, vol. 5, no. 4, pp. 339–344, 1980. 
  4. Vanhoutte, P. M., & Kruszewski, F. H., “Delta sleep-inducing peptide: biochemical and neuropharmacological properties,” Trends in Neurosciences, vol. 6, pp. 300–304, 1983. 

COA

Certificate of Analysis

HPLC

High Performance Liquid Chromatography

High Quality - 99% Purity Guaranteed

Product Quality Guarantee

We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
HPLC TEST FEE
$100
PLUS Total amount of the Order + Shipping Fee

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

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