BPC-157 (10mg) Acetylated

BPC‑157 (Body Protection Compound‑157) is a research-grade, synthetic 15‑amino‑acid peptide originally identified in human gastric juice and later synthesized for laboratory studies. Unlike many endocrine-related peptides, it's primarily examined for its potential in tissue repair, inflammation modulation, and protective mechanisms across multiple organ systems.

Chemical Structure of BPC‑157

This pentadecapeptide has the sequence: Gly–Glu–Pro–Pro–Pro–Gly–Lys–Pro–Ala–Asp–Asp–Ala–Gly–Leu–Val, with a molecular formula of C₆₂H₉₈N₁₆O₂₂ and molecular weight approximately 1,419.5 Da. It is stable under room temperature and demonstrates resilience in gastric conditions, making it viable for various routes of administration in experimental models.

What Are the Effects of BPC‑157?

• Tissue Regeneration & Wound Healing: Preclinical studies in rodents report accelerated healing of tendons, ligaments, skin wounds, and muscle injuries, correlating with increased fibroblast growth, collagen synthesis, and angiogenesis.
• Gastrointestinal Protection: Demonstrated anti‑ulcer and cytoprotective effects in gastric injury models, with regulated villus‑crypt structure and intestinal tissue preservation.
• Angiogenesis & Vascular Repair: Stimulates vascular endothelial growth factor (VEGF) signaling and nitric oxide pathways, promoting blood vessel formation in ischemic and injury models.
• Neuro‑ & Organ‑Protection: Experimental findings suggest BPC‑157 mitigates brain and nerve injury, maintains liver and kidney integrity under toxic stress, and reduces inflammatory markers.
• Anti‑Inflammatory & Oxidative Stress Reduction: Modulates nitric oxide and inflammatory cytokines, displaying both antioxidant and analgesic effects in animal research.
• Safety Profile: To date, studies report low toxicity and no significant adverse immunogenic or endocrine reactions under laboratory conditions.

Citations

1. PubChem Compound Summary for BPC‑157. BPC‑157 Molecular Structure
2. Peptide Sciences: “What is BPC‑157 Peptide?” BPC‑157 Molecular Structure
3. Front. Pharmacol.: “Stable Gastric Pentadecapeptide BPC‑157 and Wound Healing.” BPC‑157 Molecular Structure
4. J Orthop Res.: “BPC‑157 accelerates healing of transected rat Achilles tendon.” BPC‑157 Molecular Structure
5. J Appl Physiol.: “BPC‑157 promotes tendon healing through outgrowth and cell migration.” BPC‑157 Molecular Structure
6. Curr Pharm Des.: “Novel therapy in gastrointestinal tract using BPC‑157.” BPC‑157 Molecular Structure
7. Peptides.org: “BPC‑157 Reviews, Clinical Trials, and Safety.” BPC‑157 Molecular Structure
8. J Orthop Res.: “BPC‑157 improves ligament healing in the rat.” BPC‑157 Molecular Structure