HGH (10iu)

HGH, also known as somatotropin, is a peptide hormone composed of 191 amino acids. Its chemical structure includes a single polypeptide chain with two disulfide bridges. Structurally, HGH resembles the natural growth hormone produced by the human pituitary gland. The amino acid sequence of HGH is precisely coded by the GH1 gene.

HGH interacts with the body through binding to its specific receptor, the growth hormone receptor (GHR), which is predominantly located on the surface of target cells, particularly in the liver. The binding of HGH to its receptor initiates a cascade of signaling events, activating the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. This pathway, in turn, triggers the phosphorylation of various proteins, leading to the activation of downstream cellular processes.

One of the primary physiological effects of HGH is the stimulation of insulin-like growth factor 1 (IGF-1) production in the liver. IGF-1 plays a crucial role in mediating the growth-promoting effects of HGH on various tissues, including bones and muscles. Additionally, HGH influences cellular metabolism by promoting the utilization of fats for energy, sparing glucose, and contributing to the maintenance of lean body mass.

The intricate interplay of HGH and its receptor, coupled with downstream signaling cascades, underscores the complexity of its interactions within the body, orchestrating essential processes related to growth, development, and metabolism.